EXPLOITING NECROPTOSIS FOR THERAPY OF ACUTE LYMPHOBLASTIC LEUKEMIA

Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia

Escape from chemotherapy-induced apoptosis is a hallmark of drug resistance in cancer.The recent identification of alternative programmed cell death pathways opens up for possibilities to circumvent the apoptotic blockade in drug resistant Swag and Backpacks cancer and eliminate malignant cells.Indeed, we have recently shown that programmed necrosi

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Molecular pathology testing for non-small cell lung cancer: an observational study of elements currently present in request forms and result reports and the opinion of different stakeholders

Abstract Background For patients with non-small cell lung cancer (NSCLC), targeted therapies are becoming part of the standard treatment.It is of question which information the clinicians provide on test requests and how the laboratories adapt test conclusions to this knowledge and regulations.Methods This study consisted of two components; 1) chec

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Heat transfer analysis on buoyantly convective non-Newtonian stream in a hexagonal enclosure rooted with T-Shaped flipper: Hybrid meshed analysis

Chargers It is well consensus among researchers that the non-Newtonian fluid equipped in closed enclosures brings complicated mathematical models and hence one cannot examine flow field truly.The present attempt is first numerical investigation to evaluate the buoyantly convective non-Newtonian fluid flow equipped in hexagonal shaped cavity.The uni

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